In 1874, Röntgen became a lecturer at the University of Strasbourg. In 1875, he became a professor at the Academy of Agriculture at Hohenheim, Württemberg. He returned to Strasbourg as a professor of physics in 1876, and in 1879, he was appointed to the chair of physics at the University of Giessen. In 1888, he obtained the physics chair at the University of Würzburg, and in 1900 at the University of Munich, by special request of the Bavarian government.
In the late afternoon of 8 November 1895, Röntgen was determined to test his idea. He carefully constructed a black cardboard covering similar to the one he had used on the Lenard tube. He covered the Crookes–Hittorf tube with the cardboard and attached electrodes to a Ruhmkorff coil to generate an electrostatic charge. Before setting up the barium platinocyanide screen to test his idea, Röntgen darkened the room to test the opacity of his cardboard cover. As he passed the Ruhmkorff coil charge through the tube, he determined that the cover was light-tight and turned to prepare the next step of the experiment. It was at this point that Röntgen noticed a faint shimmering from a bench a few feet away from the tube. To be sure, he tried several more discharges and saw the same shimmering each time. Striking a match, he discovered the shimmering had come from the location of the barium platinocyanide screen he had been intending to use next.
8 November was a Friday, so he took advantage of the weekend to repeat his experiments and made his first notes. In the following weeks, he ate and slept in his laboratory as he investigated many properties of the new rays he temporarily termed "X-rays", using the mathematical designation ("X") for something unknown. The new rays came to bear his name in many languages as "Röntgen rays" (and the associated X-ray radiograms as "Röntgenograms").
About six weeks after his discovery, he took a picture—a radiograph—using X-rays of his wife Anna Bertha's hand. When she saw her skeleton she exclaimed "I have seen my death!" He later took a better picture of his friend Albert von Kölliker's hand at a public lecture.
According to wikipedia