[WORLDKINGS] On this day – July 5, 2023 – The 27th Anniversary of Dolly the Sheep becoming the first mammal cloned from an adult cell (1996)

05-07-2023

(Worldkings.org) On July 5, 1996, Dolly the sheep—the first mammal to have been successfully cloned from an adult cell—is born at the Roslin Institute in Scotland.

Dolly (5 July 1996 – 14 February 2003) was a female Finn-Dorset sheep and the first mammal that was cloned from an adult somatic cell. She was cloned by associates of the Roslin Institute in Scotland, using the process of nuclear transfer from a cell taken from a mammary gland. Her cloning proved that a cloned organism could be produced from a mature cell from a specific body part. Originally code-named “6LL3,” the cloned lamb was named after singer and actress Dolly Parton.

 

Dolly was born on 5 July 1996 and had three mothers: one provided the egg, another the DNA, and a third carried the cloned embryo to term. She was created using the technique of somatic cell nuclear transfer, where the cell nucleus from an adult cell is transferred into an unfertilized oocyte (developing egg cell) that has had its cell nucleus removed. The hybrid cell is then stimulated to divide by an electric shock, and when it develops into a blastocyst it is implanted in a surrogate mother. Dolly was the first clone produced from a cell taken from an adult mammal.

Dolly's existence was announced to the public on 22 February 1997. It gained much attention in the media. A commercial with Scottish scientists playing with sheep was aired on TV, and a special report in Time magazine featured Dolly. Science featured Dolly as the breakthrough of the year. Even though Dolly was not the first animal cloned, she received media attention because she was the first cloned from an adult cell.

Dolly lived at the Roslin Institute throughout her life and produced several lambs. She was euthanized at the age of six years due to a progressive lung disease. No cause which linked the disease to her cloning was found. Dolly's body was preserved and donated by the Roslin Institute in Scotland to the National Museum of Scotland, where it has been regularly exhibited since 2003.

According to Wikipedia & history.com


Kyna ( Collect) - WORLDKINGS (Source of photos: Internet)

 

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