In the early 1930s, King was doing research on the anti-scurvy effects of lemon juice on guinea pigs (guinea pigs are one of only a small group of animals besides humans who cannot produce their own vitamin C, hence they can get scurvy like us). At the same time, Hungarian physiologist Albert Szent-Gyorgyi was studying the chemical hexuronic acid that he had previously isolated from animal adrenal glands.
Within 2 weeks of each other, both King and Szent-Gyorgyi published papers on the discovery of Vitamin C, showing that the vitamin and hexuronic acid were the same compound.
Szent-Gyorgyi went on to win the Nobel Prize in Physiology or Medicine in 1937, for his part in the discovery of Vitamin C, while King was not similarly rewarded. Controversy remains over the extent to which both men deserve partial credit for the discovery.
Vitamin C is also known as ascorbic acid, thanks to its anti-scurvy properties (a- = not; scorbus = scurvy). Besides fighting off scurvy, Vitamin C has many other benefits – it is a cofactor in numerous enzymatic reactions in the body, and it has important antioxidant properties. It also enhances iron absorption, and is a natural antihistamine.
However, while it is found in high concentrations in immune cells, its flu-fighting power may be a myth. Despite extensive research, Vitamin C has not been proven effective in the prevention or treatment of colds and flu. It does not reduce the incidence or severity of the common cold, but there are some indications that it may help reduce the duration of illness.
Still, even though it may not ward away the sniffles, getting a decent daily dose will definitely do you more good than harm – there doesn’t appear to be many adverse effects from overdosing, since excessive amounts of Vitamin C is simply lost through nonabsorption or urination.
So, don’t hold back on the chilli peppers, guavas, leafy greens, broccoli, cauliflower, brussels sprouts, fresh herbs, kiwifruit, strawberries and, yes, good old oranges. And while you’re feasting away, spare a thought for Charles Glen King, the unsung hero in the Vitamin C story.
According to sciencelens